Canine CRP Test
Make useful and accurate decisions by testing for C-Reactive Protein: a general inflammation marker
The main reason for measuring C-reactive protein (CRP) is to detect and monitor systemic inflammatory activity and thus help veterinary practitioners to monitor different types of inflammatory diseases. Measurement of CRP is also an effective tool for evaluating treatment efficacy. Repeating the LifeAssays Canine CRP Test during and after treatment will show if the selected treatment (i.e. antibiotics) is effective.
C-reactive protein is a positive acute phase protein and its concentration in blood is greatly elevated in inflammation due to increased production of the protein in the liver. CRP is therefore considered a general marker for systemic inflammation and infection, and levels increase rapidly, about 4–6 hours after stimuli. If the inflammation ceases, CRP concentrations will quickly return to normal. This rapid response makes CRP an almost real-time marker for inflammatory activity and response to treatment.
Specific and objective marker for systemic inflammation (CRP)
Any change in C-reactive protein indicates a change in the inflammatory burden in the subject. CRP is present in the blood at very low concentrations in healthy individuals, often below 5 mg/L, but rises to very high concentrations during ongoing inflammation, even above 600 mg/L. Canine CRP Test uses:
- real time marker – starts after 4h, peaks after 24h and clears at 48–72h
- post-treatment assessment or to detect relapse
- elevated serum values of CRP always indicate pathology
- not induced or affected by steroid or NSAID therapy
- monitor post-operative effects and recovery
- monitor all diseases that induce a systemic inflammation, such as IMHA, IBD, leishmaniasis
Find out in just 11 minutes
When a dog gets an inflammatory disease, for example, a bacterial- or similar infection, CRP levels increase in response to the inflammation and within about 4 to 6 hours the concentration of CRP in the blood also increases. This increase is dependent on two factors:
- the severity of the inflammatory disease
- the duration of the inflammatory process
In healthy dogs, CRP levels can differ slightly between individual dogs, but are normally far below 35 mg/L. The marked difference when inflammation is present makes CRP one of the few parameters where pre-establishment of an individual animal's baseline is not necessary.
Easy-to-use point-of-care testing
LifeAssays® Canine CRP Test supports veterinarians in making decisions regarding a dog's health by enabling them to perform tests on site.
The LifeAssays® test system thereby makes quick, easy and correct test results available outside larger reference laboratories, improving services to the dog owner and giving the veterinarian a valuable diagnostic tool.
- Serum samples
- Short measurement time: 11 minutes
- Linear range: 10–210 mg/L
- Quantitative: clear relation of results to cut-off value
- Measuring range may be increased by further dilution of the sample
- Small sample volume: 5 μL
- Superior non-optical system
Canine CRP: Imprecision
|CRP mg/dL||CV (%)|
Canine CRP: Correlation
|ELISA (ICL, US)||0.98|