Feline Haptoglobin Test
Cats are an important part of many people’s lives and a big industry in many regions. We need them as much as they need us. That is why LifeAssays® AB has developed a unique patented rapid test for Feline Haptoglobin. By providing veterinary practitioners with this valuable laboratory test that can be performed in-house, early disease intervention and more effective treatment can be provided for cats, helping them to live happier and healthier lives.
Testing Acute Phase Proteins to make useful and accurate diagnoses
The immediate detection of an inflammatory response and the monitoring of its clinical course are primary challenges for veterinary medicine. The search for early inflammation markers has therefore been an important focus of veterinary medical research. Special attention has been placed on the identification of biochemical parameters that have the specificity and sensitivity to both signal the presence and evaluate the intensity of inflammatory responses. Acute Phase Proteins are a group of biological markers that show a direct response to an acute inflammation and a rapid decrease in concentrations upon removal of inflammation.
Specific and objective marker for systemic inflammation (Feline Haptoglobin)
Any change in haptoglobin indicates a change in the inflammatory burden in the subject. Haptoglobin rises to very high concentrations during ongoing inflammation, even above 600 mg/dl. Feline Haptoglobin Test uses:
- real time marker
- post-treatment assessment or to detect relapse
- elevated serum values of haptoglobin always indicate pathology
- not induced or affected by steroid or NSAID therapy
- monitor post-operative effects and recovery
- monitor all diseases that induce a systemic inflammation
Find out in just 11 minutes
When a cat gets an inflammatory disease, for example, a bacterial- or similar infection, haptoglobin levels increase and within 12 hours the concentration of haptoglobin in the blood also increases. This increase is dependent on two factors:
- the severity of the inflammatory disease
- the duration of the inflammatory process
In healthy cats, the haptoglobin levels can differ slightly between individual cats, but are normally below 250 mg/dL. The marked difference when inflammation is present makes haptoglobin one of the few parameters where pre-establishment of an individual animal's baseline is not necessary.
Easy-to-use point-of-care testing
LifeAssays® Feline Haptoglobin Test supports veterinarians in making decisions regarind the health of a cat by enabling them to perform tests on site.
The LifeAssays® test system thereby makes quick, easy and correct test results available outside larger reference laboratories, improving services to the cat owner and giving the veterinarian a valuable diagnostic tool.
- Serum samples
- Short measurement time: 11 minutes
- Linear range: 40–600 mg/dl
- Quantitative: clear relation of results to cut-off values (250)
- Measuring range may be increased by further dilution of the sample.
- Small sample volume: 5 μL
- Superior non-optical system
|Haptoglobin mg/dL||CV (%)|
How to use Feline Haptoglobin
LifeAssays® Feline Haptoglobin tests are performed on a benchtop instrument (LifeAssays® VetReader), using single-use reagent tests and a disposable algorithm chip. The chip contains all reagent identification data as well as calibration curves, providing better traceability and improved system control.
When a new reagent kit is opened, the enclosed chip is inserted into the VetReader and remains in the reader until the last reagent vial in the kit has been processed. Reagent and software upgrades are thus easily provided with each new reagent kit.
The LifeAssays® Feline Haptoglobin test system provides a quantitative measurement of feline haptoglobin in serum at the point of care, within 11 minutes. LifeAssays® Feline Haptoglobin testing helps veterinary professionals to easily integrate the measurement of haptoglobin as a point-of-care tool for diagnostics, as well as for monitoring disease progression and treatment efficacy on inflammation in cats.
Repeating the Feline Haptoglobin test during and after treatment (e.g. antibiotics) indicates whether the selected treatment has been effective and has reduced the inflammation or infection.